Cheap flights from Medellin to Panama City from $311 EOH, MDE → PTY
Enrique Olaya Herrera Airport (EOH), Jose Maria Cordova International Airport (MDE) → Tocumen International Airport (PTY)
The cheapest one-way found recently is $311 with avianca airlines, 24 Nov, found yesterday.
- Cheapest one-way found recently
- $311, avianca airlines, found yesterday
- Cheapest month to fly
- November 2026, one-way fares from $270 found in the last 7 days
- Airlines with nonstop flights
- Copa Airlines
- Shortest nonstop flight found
- 1 h 28 min
One-way
The cheapest one-way fare on each of 5 departure dates is usually $282 to $311.
Cheapest one-way found recently
$311
24 Nov · avianca airlines
Jose Maria Cordova International Airport (MDE) → Tocumen International Airport (PTY)
Leaves 12:40 p.m. · 4 h 35 min trip
1 stop · via El Dorado International Airport (BOG)
found yesterday
Cheapest nonstop one-way
$333
24 Nov · Copa Airlines
Jose Maria Cordova International Airport (MDE) → Tocumen International Airport (PTY)
Leaves 5:00 a.m. · 1 h 28 min trip
nonstop
found yesterday
Found recently, and the cheapest we hold
$311 24 Novfound yesterdayOpen this trip
$270 26 Novfound 4 days agoOpen this trip
What have prices looked like?
Over 50 days, 24 Sept to 12 Nov, the cheapest one-way we saw each day was $171 to $327.
Those were the prices on those days, not today's.
Is this a good one-way price?
Compared with the cheapest one-way fare on each of 5 departure dates from 24 Nov to 10 Feb 2027, found by travelers' searches in the last 7 days (economy, the price the seller showed on Aviasales). The usual range is the middle half of those prices.
Could nearby dates be cheaper?
Yes. Among one-way fares leaving within 3 days of 24 Nov, 26 Nov costs $270: $41 less than the cheapest found recently.
avianca airlines · Jose Maria Cordova International Airport (MDE) → Tocumen International Airport (PTY) · 1 stop · found 4 days ago
Every date we hold
31 fares on 5 departure dates
See the chart as a table
| Dates | From | Airline | Airports | Stops | Found | |
|---|---|---|---|---|---|---|
| 24 Nov | $311 | avianca airlines | Jose Maria Cordova International Airport (MDE) → Tocumen International Airport (PTY) | 1 stop | found yesterday | Open this trip |
| 26 Nov | $270 | avianca airlines | Jose Maria Cordova International Airport (MDE) → Tocumen International Airport (PTY) | 1 stop | found 4 days ago | Open this trip |
| 17 Jan 2027 | $289 | avianca airlines | Jose Maria Cordova International Airport (MDE) → Tocumen International Airport (PTY) | 1 stop | found 5 days ago | Open this trip |
| 5 Feb 2027 | $282 | avianca airlines | Jose Maria Cordova International Airport (MDE) → Tocumen International Airport (PTY) | 1 stop | found 2 days ago | Open this trip |
| 10 Feb 2027 | $391 | Clic | Enrique Olaya Herrera Airport (EOH) → Tocumen International Airport (PTY) | 2 stops | found 2 days ago | Open this trip |
Which month looks cheapest?
November 2026 is the cheapest month — from $270.
Airlines on the cheapest dates: avianca airlines, Clic.
Premium cabin fares from Medellin to Panama City
We hold no premium economy, business or first-class fares for this route: we collect them for the busiest routes, and this one is not among them yet.
Today's prices for 24 Nov in another cabin: Premium economy · Business · First
How far ahead were prices cheapest for Medellin to Panama City?
One-way
Fares 30 to 59 days before departure were typically 10% lower than 7 to 13 days before departure.
From the cheapest one-way each day between 24 Sept and 12 Nov (50 days), grouped by how many days ahead the flight left; one adult in economy.
Each range covers different departure dates, so this compares typical fares, not the same trip priced twice.
Prices reflect recent searches — current fares may differ.
See these ranges as a table
| Booked ahead by | Typical fare | Cheapest day | Above the cheapest | Days of prices |
|---|---|---|---|---|
| 7–13 days | $204 | $183 | +12% | 7 |
| 14–29 days | $264 | $171 | +44% | 28 |
| 30–59 days | $183 | $177 | Cheapest seen | 36 |
| 60–89 days | $289 | $190 | +58% | 29 |
| 90–179 days | $230 | $189 | +26% | 41 |
| 180+ days | $282 | $282 | +54% | 13 |
Could a nearby airport be cheaper?
A different airport at either end can change the fare — sometimes a lot.
One-way
Medellin → Balboa
5 km from Panama City
$128
$183 less than flying to Panama City
8 Feb 2027 · MDE → BLB · nonstop
found 3 days ago
Cheapest recent price on each route — one way, per traveler in Economy. Distances are in a straight line.
Live price for these dates
The cheapest one-way found recently is for 24 Nov. A live search on this page shows what those dates cost now, for one adult in economy.
Questions about this trip
How much is a one-way flight from Medellin to Panama City?
The cheapest one-way found recently is $311 with avianca airlines, 24 Nov, found yesterday. The cheapest one-way we hold, of any age, is $270 with avianca airlines, 26 Nov, found 4 days ago. The cheapest one-way fare on each of 5 departure dates is usually $282 to $311.
What is the cheapest month to fly from Medellin to Panama City?
November 2026 is the cheapest month for a one-way, from $270, 26 Nov, found 4 days ago.
How far ahead should I book a flight from Medellin to Panama City?
In 50 days of prices between 24 Sept and 12 Nov, one-way fares 30 to 59 days before departure were typically 10% lower than 7 to 13 days before departure.
Is there a direct flight from Medellin to Panama City?
Yes, the cheapest nonstop one-way found recently is $333 with Copa Airlines, 24 Nov, found yesterday.
How long is the flight from Medellin to Panama City?
The cheapest nonstop one-way found recently, with Copa Airlines on 24 Nov, takes 1 h 28 min from Jose Maria Cordova International Airport (MDE) to Tocumen International Airport (PTY). The cheapest one-way found recently, with avianca airlines on 24 Nov, takes 4 h 35 min with 1 stop.
Which airlines have the cheapest flights from Medellin to Panama City?
Between 24 Nov and 10 Feb 2027, avianca airlines has the cheapest one-way on 4 of the 5 departure dates we hold, and Clic on 1.
Prices are what travelers' searches on Aviasales found in the last 7 days, in US dollars: the price the seller showed on Aviasales; bags may cost extra. Fares change, so check today's price before you book. How our prices work